Osmosis Renew MD Advanced Retinal Serum

Osmosis Renew MD Advanced Retinal Serum is an advanced 30 mL vitamin A serum made for clients who are already comfortable using retinal. It helps soften the look of fine lines, rough texture and uneven tone, leaving skin looking smoother, brighter and beautifully refreshed.

A Polished Step Up for Vitamin A

Renew MD is the strongest vitamin A serum in the Osmosis professional collection. Its liposomal formula combines retinal with niacinamide, peptides, sodium hyaluronate and antioxidant-rich ingredients. The result is a thoughtful formula for skin that is ready for a more advanced routine—powerful, polished and still focused on comfort.

Why You’ll Love It

• Helps improve the appearance of fine lines and wrinkles
• Supports smoother-looking texture and a more even-looking tone
• Leaves mature or sun-exposed skin looking refreshed
• Pairs retinal with niacinamide, peptides and hydrating sodium hyaluronate
• Created for professional skincare routines and experienced vitamin A users

Who It’s For

This serum is best suited to experienced vitamin A users concerned with visible fine lines, uneven tone, dullness or rough texture. Because Renew MD is Osmosis’s strongest vitamin A option, it may not be the best first step for a new retinal user. Not sure where to begin? The Sparkle team can help you choose a routine that fits your skin.

How to Use Osmosis Renew MD

Apply two pumps, or your desired amount, to clean skin in the morning and evening. Spritz with an Osmosis Activating Mist and gently massage into the skin. Follow with additional serum and moisturizer as needed.

Sparkle Tip: New to Renew MD? Let your skin ease into the routine and ask our clinic team how often to begin. Finish your morning skincare with a broad-spectrum sunscreen.

Key Ingredients

• Retinal: A vitamin A ingredient that helps improve the look of fine lines and uneven texture.
• Niacinamide: Helps skin look balanced, smooth and bright.
• Sodium Hyaluronate: Helps attract moisture for a softer, plumper appearance.
• Ectoin: Helps support a comfortable, conditioned skin feel.
• Peptides and botanical extracts: Complete this advanced formula with added skin-conditioning care.

Full Ingredient List

Water, Niacinamide, Phosphatidylcholine, Glycerin, Pentylene Glycol, Cyclodextrin, Asiaticoside, Palmitoyl Tripeptide-38, Dipeptide-6, Retinal, Ectoin, Caprooyl Tetrapeptide-3, Thioctic Acid, Chlorella Vulgaris Extract, Epilobium Angustifolium Flower/Leaf/Stem Extract, Sodium Hyaluronate, Lactic Acid, Beta-Glucan, Fulvic Acid, Hydroxyproline, Santalum Austrocaledonicum (Sandalwood) Wood Oil, Rubus Chamaemorus (Cloud Berry) Seed Oil, Hamamelis Virginiana (Witch Hazel) Water, Dimethyl Sulfone, Pogostemon Cablin (Patchouli) Oil, Lavandula Angustifolia (Lavender) Oil, Lonicera Caprifolium (Honeysuckle) Flower Extract, Lonicera Japonica (Honeysuckle) Flower Extract, Dextran, Hydroxypropyl Cyclodextrin, Alcohol Denat., Citric Acid, Xanthan Gum, Sodium Hydroxide, Alcohol, Potassium Sorbate, Benzyl Alcohol.

Ingredient lists may change. Please check your product packaging for the most current list.

Good to Know

• Size: 30 mL / 1 fl oz
• Professional MD Advanced formula
• For external use only
• Avoid direct contact with the eyes
• If you are pregnant, breastfeeding or under medical care, ask your healthcare professional before using a vitamin A product

Frequently Asked Questions

Is Renew MD the same as a regular retinol?

No. Renew MD contains retinal, a different form of vitamin A. Osmosis uses it in this advanced professional formula.

Can a beginner use Renew MD?

Renew MD is designed for experienced vitamin A users. If you are new to retinal, ask the Sparkle team whether a gentler Osmosis option would be a better starting point.

Can I use it in the morning?

Osmosis directs users to apply it in the morning and evening. Always complete your morning routine with sunscreen.

Where does it go in my routine?

Apply Renew MD after cleansing. Add an Osmosis Activating Mist, massage gently, then follow with your other serum and moisturizer as needed.

How quickly will I notice a difference?

Skincare results vary. Consistent use and a routine suited to your skin are more important than rushing. Our clinic team can help you adjust your routine along the way.